Robert J. Lefkowitz M.D.
Keynote Speaker: Physician & Biochemist
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Robert J. Lefkowitz M.D. Biography
Dr. Lefkowitz’s memoir, A Funny Thing Happened on the Way to Stockholm, recounts his early career as a cardiologist and his transition to biochemistry, which led to his Nobel Prize win.
Robert J. Lefkowitz, M.D. is James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at the Duke University Medical Center. He has been an Investigator of the Howard Hughes Medical Institute since 1976. Dr. Lefkowitz began his research career in the late 1960’s and early 1970’s when there was not a clear consensus that specific receptors for drugs and hormones even existed. His group spent 15 difficult years developing techniques for labeling the receptors with radioactive drugs and then purifying the four different receptors that were known and thought to exist for adrenaline, so called adrenergic receptors. In 1986 Dr. Lefkowitz transformed the understanding of what had by then become known as G protein coupled receptors because of the way the receptor signal for the inside of a cell through G proteins, when he and his colleagues cloned the gene for the beta2-adrenergic receptor. They immediately recognized the similarity to a molecule called rhodopsin which is essentially a light receptor in the retina. This unexpected finding established the beta receptor and rhodopsin as the first member of a new family of proteins. Because each has a peptide structure, which weaves across the cell membrane seven times, these receptors are referred to as seven transmembrane receptors. This super family is now known to be the largest, most diverse and most therapeutically accessible of all the different kinds of cellular receptors. There are almost a thousand members of this receptor family and they regulate virtually all known physiological processes in humans. They include the receptors not only to numerous hormones and neurotransmitters but for the receptors which mediate the senses of sweet and bitter taste and smell amongst many others. Dr. Lefkowitz also discovered the mechanism by which receptor signaling is turned off, a process known as desensitization. Dr. Lefkowitz work was performed at the most fundamental and basic end of the research spectrum and has had remarkable consequences for clinical medicine. Today, more than half of all prescription drug sales are of drugs that target either directly or indirectly the receptors discovered by Dr. Lefkowitz and his trainees. These include amongst many others beta blockers, angiotensin receptor blockers or ARBs and antihistamines. Over the past decade he has discovered novel mechanisms by which the receptors function which may lead to the development of an entirely new class of drugs called “biased agonists”. Several such compounds are already in advanced stages of clinical testing. Dr. Lefkowitz has received numerous honors and awards, including the National Medal of Science, the Shaw Prize, the Albany Prize, and the 2012 Nobel Prize in Chemistry. He was elected to the USA National Academy of Sciences in 1988, the Institute of Medicine in 1994, and the American Academy of Arts and Sciences in 1988.
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How much does it cost to book Robert J. Lefkowitz M.D. for a speaking engagement?
Speaking fees for Robert J. Lefkowitz M.D., or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fee for a virtual event is $10,000 - $20,000. For the most current speaking fee to hire Robert J. Lefkowitz M.D., click the Check Schedule button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.
What topics does Robert J. Lefkowitz M.D. speak about?
Robert J. Lefkowitz M.D. is a keynote speaker and industry expert who speaks on a wide range of topics such as Authors, Medicine, Biology and Chemistry.
Where does Robert J. Lefkowitz M.D. travel from?
Robert J. Lefkowitz M.D. generally travels from Durham, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances.
Who is the agent for Robert J. Lefkowitz M.D.?
AAE Speakers Bureau has successfully secured keynote speakers like Robert J. Lefkowitz M.D. for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Schedule button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Robert J. Lefkowitz M.D. for your next private or corporate function.
What is a full-service speaker booking agency?
AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Robert J. Lefkowitz M.D. or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us.
Why is AAE Speakers Bureau different from other booking agencies?
If you’re looking for the best speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.
Robert J. Lefkowitz M.D. is a keynote speaker and industry expert who speaks on a wide range of topics including Authors, Medicine and Biology. The estimated speaking fee range to book Robert J. Lefkowitz M.D. for virtual events is $10,000 - $20,000. Please contact us for live event fees. Robert J. Lefkowitz M.D. generally travels from Durham, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Gregg L. Semenza, George Smoot and Adam G. Riess. Contact All American Speakers for ratings, reviews, videos and information on scheduling Robert J. Lefkowitz M.D. for an upcoming event.
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How do I book Robert J. Lefkowitz M.D. to speak at my event?
Our experienced booking agents have successfully helped clients around the world secure speakers like Robert J. Lefkowitz M.D. for speaking engagements, personal appearances, product endorsements, or corporate entertainment since 2002. Click the Check Schedule button above and complete the form on this page to check availability for Robert J. Lefkowitz M.D., or call our office at 1.800.698.2536 to discuss your upcoming event. One of our experienced agents will be happy to help you get speaking fee information and check availability for Robert J. Lefkowitz M.D. or any other speaker of your choice. -
How much does it cost to book Robert J. Lefkowitz M.D. for a speaking engagement?
Speaking fees for Robert J. Lefkowitz M.D., or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fee for a virtual event is $10,000 - $20,000. For the most current speaking fee to hire Robert J. Lefkowitz M.D., click the Check Schedule button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent. -
What topics does Robert J. Lefkowitz M.D. speak about?
-
Where does Robert J. Lefkowitz M.D. travel from?
Robert J. Lefkowitz M.D. generally travels from Durham, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. -
Who is the agent for Robert J. Lefkowitz M.D.?
AAE Speakers Bureau has successfully secured keynote speakers like Robert J. Lefkowitz M.D. for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Schedule button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Robert J. Lefkowitz M.D. for your next private or corporate function. -
What is a full-service speaker booking agency?
AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Robert J. Lefkowitz M.D. or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us. -
Why is AAE Speakers Bureau different from other booking agencies?
If you’re looking for the best speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.
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